Tuna is one of the most widely consumed fish on the European market, being available in various consumable options.Among them, Thunnus albacares, also called yellowfin tuna, is a delicacy and is consumed by millions of people around the world.Due to its comparatively high cost and demand, it is more vulnerable to fraud, where low-cost tuna or other

Abstract Background The regulatory roles of long non-coding RNA (lncRNA) CRNDE in temozolomide (TMZ) chemoresistance to glioblastoma multiforme (GBM) are still poorly understood.Therefore, the function, characteristics, and possible mechanism of CRNDE in TMZ-induced chemoresistance to GBM were explored.Methods Firstly, the expression level of CRNDE

Chromosomal translocations, which often generate chimeric proteins by fusing segments of two distinct genes, represent the single major genetic aberration leading to cancer.We suggest that the unifying theme of these events is a high level of intrinsic structural disorder, enabling fusion proteins to evade cellular surveillance mechanisms that elim

Challenge with specific microbial stimuli induces long lasting epigenetic changes in innate immune cells that result in their enhanced response to a second challenge by the same or unrelated microbial insult, a process referred to as trained immunity.This opens a new avenue in vaccinology to develop Trained Immunity-based Vaccines (TIbV), defined a